84-4968-64　HDAC3 (Histone Deacetylase 3) 100ul　482594

特徴

• Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.
• Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
• The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family.
• It has histone deacetylase activity and represses transcription when tethered to a promoter.
• It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.
• This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis.
• This gene is regarded as a potential tumor suppressor gene.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.