84-4958-91　GATAD2B (Transcriptional Repressor p66-beta, GATA Zinc Finger Domain Containing 2B) 100ul　481631

特徴

• Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta).
• Both proteins interact with MBD2 and MBD3 functionally and biochemically.
• Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa.
• Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern.
• These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.