84-4956-91　FXYD5 (FXYD Domain-containing Ion Transport Regulator 5) 100ul　481433

特徴

• FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids.
• The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator.
• Mouse FXYD5 has been termed RIC (Related to Ion Channel).
• FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme.
• FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems.
• Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane.
• This gene product, FXYD5, has not been characterized as a protein.
• This reference sequence was derived from AF161462.1 and ESTs; validated by multiple replicate ESTs and human genomic sequence.
• This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids.
• The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator.
• Mouse FXYD5 has been termed RIC (Related to Ion Channel).
• FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme.
• FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems.
• Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane.
• This gene product, FXYD5, has not been characterized as a protein.
• Two transcript variants have been found for this gene, and they are both predicted to encode the same protein.
• [RefSeq curation by Kathleen J.
• Sweadner, Ph.D., [email protected].].
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.