84-4939-30　DSG2 (Desmoglein-2) 100ul　479689

特徴

• Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types.
• DSG2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells.
• Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily.
• These desmoglein gene family members are located in a cluster on chromosome 18.
• This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types.
• This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells.
• Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily.
• These desmoglein gene family members are located in a cluster on chromosome 18.
• This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
• Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
• Applications:Suitable for use in Immunohistochemistry, Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.