Dgat1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.
In contrast to DGAT2 it is not essential for survival.
It may be involved in VLDL (very low density lipoprotein) assembly.
In liver, Dgat1 plays a role in esterifying exogenous fatty acids to glycerol.
It functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes DGAT1. Species Crossreactivity: bovine, canine, goat, guinea pig, equine, human, mouse, porcine, rabbit, rat, sheep
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Bo Ca Eq Gt Gp Hu Mo Po Rb Rt Sh
Immunogen：Synthetic peptide corresponding to the N-terminal region of Mouse Dgat1
