84-4934-45　DDX50 (ATP-Dependent RNA Helicase DDX50, DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 50) 100ul　479209

特徴

• DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases.
• They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.
• Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.
• DDX50 is a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing.
• DDX50 and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution.
• DDX50 gene has pseudogenes on chromosomes 2, 3 and 4.
• Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.