84-4933-55　DCTN2 (Dynactin Subunit 2, Dynactin 2 (p50)) 100ul　479120

特徴

• DCTN2 is a 50kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150kD.
• Dynactin binds to both microtubules and cytoplasmic dynein.
• It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis.
• This subunit is present in 4-5 copies per dynactin molecule.
• It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits.
• It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
• This gene encodes a 50kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150kD.
• Dynactin binds to both microtubules and cytoplasmic dynein.
• It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis.
• This subunit is present in 4-5 copies per dynactin molecule.
• It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits.
• It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.