Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1.
The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds.
They can be classified into 2 subfamilies.
In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other.
In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid.
The SDF1 proteins belong to the latter group.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity:Recognizes CXCL12.
Isotype:IgG
Calc Applications Abbrev:WB
Immunogen:Synthetic peptide corresponding to the middle region of human CXCL12