CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins.
This protein binds to the cAMP-responsive element, an octameric palindrome.
The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes.
This protein and VP16 both bind to the same site on host cell factor C1.
It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection.
An additional transcript variant has been identified, but its biological validity has not been determined.This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins.
This protein binds to the cAMP-responsive element, an octameric palindrome.
The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes.
This protein and VP16 both bind to the same site on host cell factor C1.
It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection.
An additional transcript variant has been identified, but its biological validity has not been determined.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity:Recognizes human CREB3.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to the middle region of human CREB3