84-4926-37　COQ3 (Hexaprenyldihydroxybenzoate Methyltransferase, Mitochondrial, Coenzyme Q3 Homolog, Methyltransferase (S. Cerevisiae)) 100ul　478407

特徴

• Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]).
• This lipid consists of a hydrophobic isoprenoid tail and a quinone head group.
• The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane.
• The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain.
• The S.
• cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q.
• This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q.
• The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.