This gene encodes a member of the p34Cdc2 protein kinase family.
p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control.
This gene is in close proximity to CDC2L1, a nearly identical gene in the same chromosomal region.
The gene loci including this gene, CDC2L1, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions, which are thought to be a part of the larger region that has been duplicated.
This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes.
The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis.
Many transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of only two have been determined so far.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
