84-4916-87　CD1E (T-Cell Surface Glycoprotein CD1e, Membrane-Associated, CD1e Molecule) 100ul　477466

特徴

• This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.
• The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.
• The human genome contains five CD1 family genes organized in a cluster on chromosome 1.
• The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands.
• The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form.
• The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.
• Many alternatively spliced transcript variants encoding different isoforms have been described.
• Additional transcript variants have been found; however, their biological validity has not been determined.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.