This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.
The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.
The human genome contains five CD1 family genes organized in a cluster on chromosome 1.
The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands.
The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system.
Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
