At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane.
CBX3 binds DNA and is a component of heterochromatin.
CBX3 also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane.
The dual binding functions of CBX3 may explain the association of heterochromatin with the inner nuclear membrane.At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane.
The protein encoded by this gene binds DNA and is a component of heterochromatin.
This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane.
The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.
Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes human CBX3.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the middle region of human CBX3
