BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family.
Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase.
The predicted human protein is 92% identical to mouse BPntase.
BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways.
The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family.
Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase.
The predicted human protein is 92% identical to mouse BPntase.
BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways.
The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes human BPNT1.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the N-terminal region of human BPNT1
