It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia.
The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins.
This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.
The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity:Recognizes human BCL3.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to a fragment of residues within the following region: PASTSQPDPSPDRSANTSPESSSRLSSNGLLSASPSSSPSQSPPRDPPGF