P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes.
Several subfamilies of P-type ATPases have been identified.
One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+).
Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+).
A third subfamily transports amphipaths, such as phosphatidylserine.P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes.
Several subfamilies of P-type ATPases have been identified.
One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+).
Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+).
A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM].