84-4898-75　ARRB2 (Beta-Arrestin-2, Arrestin, Beta 2) 100ul　475670

特徴

• Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals.
• ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro.
• It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors.
• Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals.
• Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro.
• It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors.
• Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.
• Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
• Applications:Suitable for use in Immunohistochemistry, Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.