APCS is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization.
These family members have considerable sequence homology which is thought to be the result of gene duplication.
The binding of the protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone.
This protein is also thought to control the degradation of chromatin.
It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization.
These family members have considerable sequence homology which is thought to be the result of gene duplication.
The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone.
This protein is also thought to control the degradation of chromatin.
It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
This gene has multiple polyadenylation sites.
Applications:Suitable for use in Immunohistochemistry, Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity:Recognizes human APCS.
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to the N-terminal region of human APCS