Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion.
It is an important effector controlling blood pressure and volume in the cardiovascular system.
It acts through at least two types of receptors.
AGTR1 is the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II.
AGTR1 may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium.
It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans.Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion.
It is an important effector controlling blood pressure and volume in the cardiovascular system.
It acts through at least two types of receptors.
This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II.
This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium.
It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans.
At least five transcript variants have been described for this gene.
Additional variants have been described but their full-length nature has not been determined.
The entire coding sequence is contained in the terminal exon and is present in all transcript variants.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes human AGTR1.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the N-terminal region of human AGTR1
