84-4887-84　ACKR2 (Chemokine-binding Protein 2) 100ul　474590

特徴

• CCBP2 is a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors.
• Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site.
• The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors.
• This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown.This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors.
• Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site.
• This gene is expressed in a range of tissues and hemopoietic cells.
• The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors.
• This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown.
• This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
• Applications:Suitable for use in Immunohistochemistry, Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.