84-4886-54　ABCB7 (ATP-binding Cassette Sub-family B Member 7, Mitochondrial Ensembl ENSP00000343849, ATP-binding Cassette, Sub-family B (MDR/TAP), Member 7) 100ul　474461

特徴

• The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.
• ABC proteins transport various molecules across extra- and intra-cellular membranes.
• ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
• This protein is a member of the MDR/TAP subfamily.
• Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation.
• This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol.
• With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis.
• Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia.
• Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.