In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda.
The ratio of Kappa to Lambda is 70:30.
However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed.
Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Applications:Suitable for use in Immunoelectrophoresis.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Total Protein:2.9g/dL
Titer:5.7mg/mL (IFCC)
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：10ml
Host：goat
Source Antibody：human
Grade：Purified
Purity：Defibrinated, delipidated, fractionated and adsorbed by solid phase chromatography.
Form：Supplied as a liquid in Tris, pH 7.4, 0.5M sodium chloride, 0.09% sodium azide.
Specificity：Recognizes Lambda Light Chains. Monospecific by IEP with neat antibody when tested against pooled human plasma and twice concentrated human serum. No reaction to Kappa Light Chains by Ouchterlony.
