ApoE is a 35-40kD protein component of serum chylomicrons, VLDL, and HDL particles.
It mediates the binding, uptake, and catabolism of these particles through interactions with the ApoE receptor and LDL receptors in the liver and brain.
ApoE is important in fatty acid homeostasis and memory formation.
Polymorphisms encode three variants (ApoE2, 3, 4) which are differentially related to the development of atherosclerosis and neurogenerative disorders.
Mature human ApoE shares 71% aa sequence identity with mouse and rat ApoE.
Applications:Suitable for use in IEP.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：10mg
Host：goat
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography from serum.
Form：Supplied as a liquid in Tris, pH 7.4, 250mM sodium chloride, 15mM sodium azide.
