The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family.
The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration.
This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation.
The expression of this gene can be induced by tumor necrosis factor alpha and interleukin-1.
The expression can also be induced by mechanical stimuli in vascular smooth muscle cells, and is found to be correlated with proteoglycan synthesis and aggregation.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MIILIYLFLLLWEDTQGWGFKDGIFHNSIWLERAAGVYH REARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKI GFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYG IRLNRSERWDAYCYNPHAKECGGVFTDPKQIFKSPGF PNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCL ADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTL KFLSDASVTAGGFQIKYVAMDPVSKSSQGKNTSTTST GNKNFLAGRFSHL
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：mouse
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.4.
Specificity：Recognizes human TNFAIP6
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Protein corresponding to aa1-277 from full length human TNFAIP6
