Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain,homologous to the HMG box of sex-determining region Y (SRY).
Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes.
SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements.
The protein encoded by this gene was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MVQQRGARAKRDGGPPPPGPGPAEEGAREPGWCKT PSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEIS KRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYK YRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLPG RGGRRAAGGPLGGGAAAPEDDDEDDDEELLEVRLVE TPGRELWRMVPAGRAARGQAERAQGPSGEGAAAAA AASPTPSEDEEPEEEEEEAAAAEEGEEETVASGEESL GFLSRLPPGPAGLDCSALDRDPDLQPPSGTSHFEFPD YCTPEVTEMIAGDWRPSSIADLVFTY
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
