This gene is a member of the iron/manganese superoxide dismutase family.
It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit.
This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen.
Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.
Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MLSRAVCGTSRQLAPALGYLGSRQKHSLPDLPYDYGA LEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAK GRFQAERREAVPGRGDPREPGPIRTGLSVEENSLRIC TGSEFSRHDSLSFKHMVYLIVEGVPRWV
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：mouse
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.4.
Specificity：Recognizes human SOD2
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Protein corresponding to aa1-140 from full length human SOD2.
