This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region.
One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD).
The transcripts are imprinted and are paternally expressed in the limb and eye.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVE ALYLVCGERGFFYTPKTRREAEDLQASALSLSSSTST WPEGLDATARAPPALVVTANIGQAGGSSSRQFRQRAL GTSDSPVLFIHCPGAAGTAQGLEYRGRRVTTELVWEE VDSSPQPQGSESLPAQPPAQPAPQPEPQQAREPSPE VSCCGLWPRRPQRSQN
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:mouse
Source Antibody:human
Grade:Purified
Purity:Purified
Form:Supplied as a liquid in PBS, pH 7.4.
Specificity:Recognizes human NS-IGF2.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Protein corresponding to aa1-200 from full length human INS-IGF2.