84-4881-89　HMGCS2 50ug　470025

特徴

• Mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase (HMGCS2; EC 2.3.3.10) mediates the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for brain, heart, kidney, and other organs during times of carbohydrate deprivation such as fasting (Robinson and Williamson, 1980 [PubMed 6986618]).
• Also see cytoplasmic HMG-CoA synthase (HMGCS1; MIM 142940), which mediates an early step in cholesterol synthesis.[supplied by OMIM]
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MQRLLTPVKRILQLTRAVQETSLTPARLLPVAHQRFST ASAVPLAKTDTWPKDVGILALEVYFPAQYVDQTDLEKY NNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRL MERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQD SGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDG RYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPL ALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCY LRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMI FHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLE AFGGLKLEDTYTNKDLDKALLKASQDMFDKKTKASLYL STHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFS YGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKR LASRKCVSPEEFTEIMNQREQFYHKVNFSPPGDTNSL FPGTWYLERVDEQHRRKYARRPV
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.