The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A.
The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains.
Mutant beta globin causes sickle cell anemia.
Absence of beta chain causes beta-zero-thalassemia.
Reduced amounts of detectable beta globin causes beta-plus-thalassemia.
The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYP WTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFS DGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVL VCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：mouse
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.4.
Specificity：Recognizes human HBB.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Protein corresponding to aa1-147 from full length human HBB.
