84-4881-68　GRB10 (GRB-IR, Grb-10, IRBP, KIAA0207, MEG1,RSS) 50ug　470004

特徴

• The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules.
• This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors.
• Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression.
• This gene is imprinted in a highly isoform- and tissue-specific manner.
• Alternatively spliced transcript variants encoding different isoforms have been identified.
• [provided by RefSeq]
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASG PPRSIQPQVSPRQRVQRSQPVHILAVRRLQEEDQQFR TSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQD VKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDD NSWTLVEHHPHLGLERCLEDHELVVQVESTMASESKF LFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQ LLQNFLNSSSCPEIQGFLHVKELGKKSWKKLYVCLRRS GLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQYN APTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMT AFRLLKYGMLLYQNYRIPQQRKALLSPFSTPVRSVSEN SLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRS TRMNILGSQSPLHPSTLSTVIHRTQHWFHGRISREESH RIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNF QILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGV LPCKLKHHCIRVAL
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.