Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin.
Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A,and 3B.
Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas.
To date, elastase 1 expression has only been detected in skin keratinocytes.
Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISL QYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFR VVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAA GYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYI TGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWG STVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKY SVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIA SN
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：mouse
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.4.
Specificity：Recognizes human ELA1.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Protein corresponding to aa1-258 from full length human ELA1.
