This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes.
They encode type II membrane-bound glycoproteins thatappear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl.
Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures.
As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor.
By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7.
The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins.
Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue.
Two transcript variants encoding the same protein have been found for this gene.
[provided by RefSeq]
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MPSTQLLAAAAAAATAPGPTPPPLAPGSLRSPVPCPV PRLPRCHPVLTRHLVLRVHRENPGVLMGGRYTPPDCT PAQTVAVIIPFRHREHHLRYWLHYLHPILRRQRLRYGV YVINQHGEDTFNRAKLLNVGFLEALKEDAAYDCFIFSD VDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYAG YFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRI SLTGMKVSRPDIRIGRYRMIKHDRDKHNEPNPQRFTKI QNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITVDIGRP PSWPPRG
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：mouse
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.4.
Specificity：Recognizes human B4GALT2
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Protein corresponding to aa1-306 from full length human B4GALT2
