84-4878-63　TWIST2 (Twist-related Protein 2, Class A Basic Helix-loop-helix Protein 39, bHLHa39, Dermis-expressed Protein 1, Dermo-1, TWIST2, BHLHA39, DERMO1) 100ul　407255

特徴

• Binds to the E-box consensus sequence 5￥'-CANNTG-3￥' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C.
• Also represses expression of proinflammatory cytokines such as TNFA and IL1B.
• Involved in postnatal glycogen storage and energy metabolism (By similarity).
• Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
• Applications:Suitable for use in ELISA, Immunofluorescence, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunofluorescence: 1:50-1:200Immunohistochemistry: 1:20-1:200 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.