84-4870-69　PACSIN2 (Protein Kinase C and Casein Kinase Substrate in Neurons Protein 2, Syndapin-2, Syndapin-II, PACSIN2) 100ul　406862

特徴

• Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds.
• Plays a role in intracellular vesicle-mediated transport.
• Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus.
• May also play a role in the formation of caveolae at the cell membrane.
• Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000-1:5000Immunohistochemistry: 1:20-1:200 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.