84-4869-06　NDUFA13 (NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Subunit 13, Cell Death Regulatory Protein GRIM-19, Complex I-B16.6,CI-B16.6, Gene Associated with Retinoic, Interferon-Induced Mortality 19 Protein, GRIM-19, Gene Associated with Retinoic, IFN-Induced Mortality 19 Protein, NADH-Ubiquinone Oxidoreductase B16.6 Subunit, GRIM19, CDA016, CGI-39) 100ul　406781

特徴

• Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
• Complex I functions in the transfer of electrons from NADH to the respiratory chain.
• The immediate electron acceptor for the enzyme is believed to be ubiquinone.
• Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death.
• This apoptotic activity is inhibited by interaction with viral IRF1.
• Prevents the transactivation of STAT3 target genes.
• May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000-1:5000Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.