84-4867-55 MESP2 (Mesoderm Posterior Protein 2, Class C Basic Helix-loop-helix Protein 6, bHLHc6, MESP2, BHLHC6, SCDO2) 50ul 406707
特徴
- Transcription factor with important role in somitogenesis.
- Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways.
- Regulates also the FGF signaling pathway.
- Specifies the rostral half of the somites.
- Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand.
- Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling.
- Acts as a strong suppressor of Notch activity.
- Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.
- Applications:Suitable for use in ELISA.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：50ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes human MESP2.
- Isotype：IgG
- Calc Applications Abbrev：E
- Calc Crossreactivity：Hu
- Immunogen：Recombinant protein corresponding to aa218-397 of human MESP2.
- Shelf Life：1year
- Swiss Prot Number：Q0VG99
- EU Commodity Code：30021010
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