84-4867-45　MEMO1 (Protein MEMO1, C21orf19-like Protein, Hepatitis C Virus NS5A-transactivated Protein 7, HCV NS5A-transactivated Protein 7, Mediator of ErbB2-driven Cell Motility 1, Mediator of Cell Motility 1, Memo-1, MEMO1, C2orf4, MEMO, NS5ATP7, CGI-27) 50ul　406702

特徴

• May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton.
• Mediator of ERBB2 signaling.
• The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex.
• It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.
• In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
• Is required for breast carcinoma cell migration.
• Applications:Suitable for use in ELISA, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: 1:20-1:200 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.