84-4865-85　KHDRBS3 (KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 3, RNA-Binding Protein T-Star, Sam68-Like Mammalian Protein 2, SLM-2, Sam68-Like Phosphotyrosine Protein, SALP, SLM2) 50ul　406623

特徴

• RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion.
• May play a role as a negative regulator of cell growth.
• Inhibits cell proliferation.
• Involved in splice site selection of vascular endothelial growth factor.
• Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer.
• RNA-binding abilities are down-regulated by tyrosine kinase PTK6.
• Involved in post-transcriptional regulation of HIV-1 gene expression.
• Binds preferentially to the 5￥'-[AU]UAAA-3￥' motif in vitro.
• Applications:Suitable for use in ELISA, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.