84-4860-71　DTX2 (Probable E3 Ubiquitin-Protein Ligase DTX2, Protein Deltex-2, Deltex2, hDTX2, RING Finger Protein 58, KIAA1528, RNF58) 100ul　406368

特徴

• Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations.
• Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context.
• Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1.
• Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000-1:5000Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.