Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity.
Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells.
Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3.
Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT.
Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner.
Also involved in striated muscle regeneration and repair and in the regulation of cell spreading (By similarity).
Important for the maintenance of cardiac function.
Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density.
Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
Applications:Suitable for use in Immunofluorescence, ELISA.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human BVES.
Isotype：IgG
Calc Applications Abbrev：E IF
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to aa241-360 of human BVES.
