CIDE-C (also known as cell death-inducing DFFA-like effector-c, CIDE-3 or Fsp27), is a 238 amino acid protein that localizes to the cytoplasm and contains one CIDE-N domain.
Expressed predominately in small intestine, colon, heart and stomach, and is present at lower levels in liver, brain and kidney.
CIDE-C exists as three alternatively spliced isoforms, two of which are thought to induce apoptosis.
Additionally, CIDE-C is upregulated during adipogenesis in white and brown adipose tissue, and may negatively regulate lipolysis and promote triglyceride accumulation.
The gene encoding CIDE-C maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
Applications:Suitable for use in Immunohistochemistry, Immunofluorescence, ELISA.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:100-1:500 ELISA: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CIDEC.
Isotype：IgG
Calc Applications Abbrev：E IF IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human CIDEC.
