CD2BP2 (CD2 (cytoplasmic tail) binding protein 2), also known as LIN1, Snu40, FWP010 or U5-52K, is a 341 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one GYF domain.
Expressed in a variety of tissues, CD2BP2 exists as a bifunctional protein that, in the nucleus, is a component of the U5 small nuclear ribonucleoprotein complex and, in the cytoplasm, binds to the tail of the CD2 antigen.
Via its multifunctional activity, CD2BP2 participates in RNA splicing and regulates CD2-triggered T-lymphocyte activation.
The gene encoding CD2BP2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome.
Applications:Suitable for use in Western Blot, ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000 ELISA: 1:40,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes endogenous levels of human CD2 Tail-binding.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human CD2 Tail-binding.
