84-4690-63　PROC (Vitamin K-Dependent Protein C, Anticoagulant Protein C, Autoprothrombin IIA, Blood Coagulation Factor XIV, Vitamin K-Dependent Protein C Light Chain, Vitamin K-Dependent Protein C Heavy Chain, Activation Peptide) 100ug　397526

特徴

• Protein C(PROC), also called PC, is a zymogenic (inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals.
• The PROC gene is mapped on 2q14.3.
• This gene encodes a vitamin K-dependent plasma glycoprotein.
• The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex.
• This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII.
• Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
• Applications:Suitable for use in ELISA, Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 0.1-0.5ug/mlWestern Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.