84-4690-07　LGALS3BP (Galectin-3-Binding Protein, Basement Membrane Autoantigen p105, Lectin Galactoside-Binding Soluble 3-Binding Protein, Mac-2-Binding Protein, MAC2BP, Mac-2 BP, Tumor-Associated Antigen 90K, M2BP) 100ug　397468

特徴

• Galectin-3-binding protein is a protein that in humans is encoded by the LGALS3BP gene.
• The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions.
• LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV).
• It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity.
• Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25.
• The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlImmunohistochemistry (paraffin): 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.