Galectin-1 is a protein that in humans is encoded by the LGALS1 gene.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions.
Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation.
Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells.
It is thought to play a role in creating immune tolerance in pregnancy.
It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV.
Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA (Capture): 2-8ug/mlELISA (Detection): 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in 5mg/ml BSA, 0.9mg sodium chloride, 0.2mg Na2HPO4, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O to ~0.5mg/ml.
Specificity：Recognizes mouse Lgals1.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to mouse Lgals1, (Position: A2-E135), expressed in E. coli.
