IL17C, also known as CX2, is a protein that in humans is encoded by the IL17C gene.
IL17C is mapped to 16q24.3.
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17.
This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line.
The expression of this cytokine was found to be restricted to activated T cells.
IL17C is an essential autocrine cytokine regulating innate epithelial immune responses.
It also plays an important role in the pathogenesis of inflammatory arthritis.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1-5ug/mlWestern Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder in 5mg/ml BSA, 0.9mg sodium chloride, 0.2mg Na2HPO4, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O to ~0.5mg/ml.
Specificity:Recognizes mouse Il17c. Species Crossreactivity: rat.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Mo Rt
Immunogen:Recombinant protein corresponding to mouse Il17c, (Position: H15-Q194), expressed in E. coli.