Dynamin-2 is a protein that in humans is encoded by the DNM2 gene.
Dynamins represent one of the subfamilies of GTP-binding proteins.
These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain.
Dynamins are associated with microtubules.
They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts.
Dynamins bind many proteins that bind actin and other cytoskeletal proteins.
Dynamins can also self-assemble, a process that stimulates GTPase activity.
Five alternatively spliced transcripts encoding different proteins have been described.
Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 0.1-0.5ug/mlWestern Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in 4mg trehalose, 0.9mg sodium chloride, 0.2mg Na2HPO4, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O to ~0.5mg/ml.
Specificity：Recognizes human DNM2. Species Crossreactivity: mouse, rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Recombinant protein corresponding to human DNM2, (Position: A177-Q441), expressed in E. coli.
