84-4688-83　BMP4 (Bone Morphogenetic Protein 4, BMP-4, Bone Morphogenetic Protein 2B BMP-2B, BMP2B, DVR4) 100ug　397339

特徴

• Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene.
• It is found on chromosome 14q22-q23.
• The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily.
• The superfamily includes large families of growth and differentiation factors.
• Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site.
• This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.
• Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
• Applications:Suitable for use in ELISA, Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1-5ug/mlWestern Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.