IL-17A is a 35kD disulfide-linked homodimer consisting of two 153aa chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217).
IL-17, originally thought to have been produced primarily by activated CD4+ T cells, appears to have a range of cellular origins and induces a variety of target cells to secrete inflammatory cytokines, including IL-1 beta, IL-6, TNF alpha, IFN gamma and granulocyte colonystimulating factor, as well as synergizing with other inflammatory cytokines and agonists.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1-10ug/mlWestern Blot: 0.1-1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：bovine
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography from whole serum.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes bovine IL-17A. Species Crossreactivity: dolphin, sheep, porcine, canine, equine.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Bo Ca Eq Po Sh
Immunogen：Recombinant protein corresponding to bovine IL-17A.
